Scalable Parameter Estimation for Genome-Scale Biochemical Reaction Networks
نویسندگان
چکیده
منابع مشابه
Scalable Parameter Estimation for Genome-Scale Biochemical Reaction Networks
Mechanistic mathematical modeling of biochemical reaction networks using ordinary differential equation (ODE) models has improved our understanding of small- and medium-scale biological processes. While the same should in principle hold for large- and genome-scale processes, the computational methods for the analysis of ODE models which describe hundreds or thousands of biochemical species and ...
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ژورنال
عنوان ژورنال: PLOS Computational Biology
سال: 2017
ISSN: 1553-7358
DOI: 10.1371/journal.pcbi.1005331